The Approach to an Abnormal Platelet Count | Consultant360 Platelets: a critical link between inflammation and ... Normal Platelet count ↓ Platelet Function : . Normal iron stores, sedimentation rate and cytogenetics ... What could be some causes of a high platelet count ... Symptoms of thrombocytopenia A general guide to what you might experience at different platelet counts is: slightly low platelet count (above 50): you will probably have no symptoms at all. A high platelet count can be identified through routine blood tests. 10 Causes of High Platelet Count - Thrombocyte If you've had significant blood loss from a recent surgery or an injury, your elevated platelet count might resolve on its own. High platelets is a condition in which the blood contains more platelets than normal. High WBC and platelet count | Mayo Clinic Connect As long as you are within the accepted range—150,000 to 400,000 (or a little more; like I said 425,000 is still normal). That is a very wide range. 150,000-450,000. low platelet level (thrombocytopenia) less than 150,000. Dr. Keith Stockerl-Goldstein answered. Platelets come from the same blood-forming cells that make other blood cells. 5) Autoimmune Disorders Autoimmune disorders can impair bone marrow function, decrease platelet production, or increase the destruction of platelets [ 18 , 19 , 20 ]. Overview: Thrombocytosis, also called thrombocythemia, is generally defined as a platelet count greater than a defined upper limit of normal that may vary between 350,000/μl to 600,000/μl, depending on the laboratory or medical reference. The hemoglobin level dropped slightly after initial hydration, but by day 8, it was 10 g/dL. A slightly elevated level of MCV on a CBC signifies macrocytic anemia, a diagnosis of abnormally large blood cells. The great part is that your levels . A reaction to a disease. The most common cut off for normal is <450,000/μl. Normal platelet counts are in the range of 150,000 to 400,000 per microliter (or 150 - 400 x 109 per liter), but the normal range for the platelet count varies slightly among different laboratories. Should we delve further into the elevated platelet count or go with the dr. and pass it off as normal? If your Platelet count is just slightly above 400k, say 400,005, then this should not be of any concern. Normal platelet counts are in the range of 150,000 to 400,000 per microliter (or 150 - 400 x 109 per liter), but the normal range for the platelet count varies slightly among different laboratories. I've just had a call from my doctor requesting a repeat blood test due to a slightly elevated platelet count. Is it normal to have slightly elevated platelets count ... Those receiving romiplostim by single IV injection at 10 µg/kg showed elevated platelet counts at over 1000 × 10 9 /l. Is 490 a high platelet count? Certain medicines. I have 3 different solid cancers as well as Chronic Lymphocytic Leukaemia (CLL) so my WBC count is a bit higher at 150 and my Platelets range between 150 to 200. Readings of the mean corpuscle hemoglobin, MCH, within the range of 27 to 31 picograms per cell are considered normal. No specific complaints had prompted her visit—it was for a routine examination, blood . Elevated platelets, also called thrombocytosis is a relatively common finding. Is 530 a high platelet count? The first study in patients with ITP used a dose of 0.2-10 µg/kg on days 1 and day 15 . On day 5, an iron tablet was prescribed. I, too have elevated platelet counts. For instance: PLT count 400 is high count but still within preset normal levels. If it remains persistently high or show a rising trend, then it can be an inflammatory condition like rheumatoid arthritis. Both high platelet counts and low platelet counts can have associated risks that can range from either not causing any noticeable health problems to being very serious and life-threatening. The ideal platelet range is 150,000 to 400,000 per mcL in most healthy people. Increased platelet counts (thrombocytosis) are rarely cause for any concern, especially if the rest of the complete blood count is normal. Normal Platelet Count for teenager 14 years must be a value from 176 to 452 to be considered healthy. Thrombocytosis describes an elevated platelet count above 400,000 per ml. I have had a low grade fever between 99-100.3 degrees since last Dec. every day. Treatment for this condition depends on the cause. This can be due to dehydration or an incidental finding. How high is the highest that platelets can go .some of the nurses that call me back with my platelet count when it's at 500,000 say it's only slightly elevated don't worry but when I see a hematologist they look at you as if it's the end of the world so I get conflicting outcomes This elevation can be extreme, with platelet counts greater than 1 million cells per microliter. If you just got over a bad infection, your platelet count will be higher. Here is a list of diseases and disorders which can raise the WBC count of an individual. A bone marrow aspirate and biopsy are performed and reveal a normocellular marrow. Causes may include: Iron deficiency. Normally WBC range should be between 4 to 11 and platelets 150 to 400. Slightly high platelet count. Health care providers typically use a test known as a complete blood count (CBC) to measure the number of red and white blood cells and platelets within a particular blood sample. Blood is a fairly complex substance that requires a pretty strict . Platelet count. High Platelet Count . •Platelets are responsible for primary hemostasis and wound healing •Normal platelet count is 150,000/μL to 450,000/μL •Bleeding due to thrombocytopenia is typically mucocutaneous •Oral, GI, GU, skin •Moderate-severe bleeding typically occurs with counts <20,000/μL The white population was found to have a higher white blood cell . A high platelet count is 400,000 (400 × 10 9 /L) or above. In looking back at my labs over the last 10 years I've had slightly elevated platelets--somewhere around 25 to 50 points higher than the max normal range. If you've had significant blood loss from a recent surgery or an injury, your elevated platelet count might resolve on its own. I am currently using the following:- Test ace 50mg eod Tren ace 100mg eod Mast p 100mg eod My question is, what could be causing the elevated . A normal platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. I have had chronic pain (approximately 3 years) in my neck and shoulders. Platelet counts decreased by 12% after a 3 -month stay at high altitude and by 31% after a 13-month stay in comparison to sea level counts . Yes: Any inflammatory condition can cause reactive increase in platelet count but to only a certain extent. People with thrombocytosis often don't have signs or symptoms. How high r ur platelets? If you have a chronic infection or an inflammatory disease, your platelet count likely will remain high until the condition is under control. I have become aware of joint pain (all of my joints) over the last year; the pain has become constant over the last six . The nurse practitioner at the hematology office stated I have no reason to be concerned, as these are very minor elevations and my white count is usually normal (occasionally slightly elevated). Blood platelet counts at the higher end of normal suggest a high risk of cancer in men aged 60 or over, and should be investigated, according to new University of Exeter research. Red blood cells are one of the major components of blood, along with white blood cells and platelets. FYI the WHO diagnostic criteria for essential thrombocythemia is platelet count over 450 and a positive test for one of 3 genetic mutations (JAK2, CalR or MPL) and a positive bone marrow biopsy. This is usually because there's a problem with one of the genes that control the making of platelets. In some cases of thrombocytosis, the platelet count can increase into as high as 750,000 per microliter of blood. After your next blood test, your doctor may advise a "watch and see" - just regular blood testing to keep an eye on things. An elevated platelet count is known as thrombocytosis. Created with Raphaël 2.1.4. Certain types of leukemia (cancer of blood forming tissues), for example, Acute Lymphocytic . Dizziness or lightheadedness. Low platelet count is what would be associated with abnormal bleeding, and that would also be exacerbated by taking aspirin or blood thinners. Platelets not only prevent bleeding injuries but they also promote proper blood circulation in the body. Rapid destruction or overuse of platelets (possibly due to infection or autoimmune problems) Excess, or trapped, platelets in the spleen. platelet counts • If platelets are low secondary to bone-marrow failure usually there will be a hemostatic defect • Template bleeding time if properly performed can assess in vivo platelet effectiveness - Thrombocytosis, if secondary to myeloproliferative disorder • Post-splenectomy thrombocytosis usually not a problem Dizziness or lightheadedness. Mild to moderately elevated platelet counts are commonly seen when chronic inflammation is present. Answer (1 of 3): Platelet counts of 425,000 and 380,000 are normal counts. I also show hi-normal neutrophils in many of my labs, or there's a higher number of neutrophils but no lab range. The platelet count is marginally on the higher side. This is because slightly elevated platelet counts rarely cause any major problems, and they have many causes. Moderately high platelet counts such as yours sometimes means that another inflammatory disease or infection is ongoing. A higher-than-normal number of platelets is called thrombocytosis. The majority of people who experience this are asymptomatic but a small group of patients with other risk factors may develop blood clots . A normal platelet count is about 150,000 to 400,000 per milliliter of blood. Red blood cells help carry oxygen throughout the body. If you've had something like a stroke or other clotting issue, they'll take that into account. Answer. The platelet count remains elevated at 625,000/ml. My counts were consistently high for years (never had a normal CBC) and I wasn't diagnosed until my platelets hit a million. When it comes to the causes of high platelet count, in some cases it can be some underlying condition, such as inflammation, infection, surgery or injury, or, in the worst cases, this condition can be caused by some disease of the blood or bone marrow, such as anemia or cancer. A slight elevation of the MCH level signifies a higher than usual amount of hemoglobin in the red blood cells. It may indicate a recent history of bleeding (unlikely with your dog's normal history) and very rarely is an indicator of a particular type of bone marrow disease called Megakaryocytic Leukemia. In most cases, your platelet count will . High platelet count is known as thrombocytosis. An elevated platelet count greater than 2 SD defines a condition of thrombocytosis. High platelet counts can lead to stroke, heart attack, or a blood clot in a vein. Thrombocytes are smaller than red and white blood cells. Platelets . This test measures the number of red blood cells, white blood cells and platelets in a sample of blood. Sometimes blood-forming cells just make too many platelets. You received your blood test result with a Platelets value of 432 x10E3/uL. Mild to moderately elevated platelet counts are commonly seen when chronic inflammation is present. In most cases, your platelet count will . Take care, Michelle in CA People with essential thrombocythemia might have signs and symptoms related to blood clots and bleeding, including: Headache. High MPV/normal platelet count - It occurs in people with chronic myelogenous leukemia (cancer) and hyperthyroidism. The Possible Causes of High Platelet Count. Signs and symptoms of reactive thrombocytosis, if they do occur, relate to the underlying condition. Having elevated platelet counts can be associated with cancer, with one study reporting that about 11% of men with high platelets and about 6% of women with high platelets had cancer. undefined 21 years experience. Explore which cancers patients with high-normal counts are most at risk of, and the cancer staging at diagnosis. Your platelet count is not very high - just slightly above the "normal" level. Some other causes of low platelet counts include: 1. Doctors measure your red blood cell count to help diagnose medical conditions and learn more about your health. A reaction to a disease. Normal platelet counts are in the range of 150,000 to 400,000 per microliter (or 150 - 400 x 109 per liter), but the normal range for the platelet count varies slightly among different laboratories. Thrombocytosis is treated with medications that inhibit platelet production in bone marrow. In general, a platelet count more than 450,000 cells per microliter is considered elevated; this is known as thrombocytosis. People with thrombocytosis often don't have signs or symptoms. I have had slightly elevated platelets, in the 390 - 440,000 range that we've been following for 10 years with bi annual blood tests. After certain infections, major surgery or trauma. This is because slightly elevated platelet counts rarely cause any major problems, and they have many causes. If you have a chronic infection or an inflammatory disease, your platelet count likely will remain high until the condition is under control. 3. As a matter of fact, counts change almost daily. I have a slightly elevated platelet count of 409. Elevated platelets in a person's blood work may indicate reactive thrombocytosis. What causes a platelet count to be slightly elevated? A high platelet count is not considered medically significant until the count is above 450K, normally. A high platelet count is called thrombocytosis. (5, 6, and 7) MPV blood test high. Platelets come from the same blood-forming cells that make other blood cells. You need to have your platelet count anywhere between 150,000 and 450,000/mcL, but certain health conditions can push your platelet count up, which can cause serious complications. Elevated White Blood Cell Counts Should Be Monitored Since white blood cells help fight disease, viruses, and infections, you may assume that an elevated white blood cell count is a good thing. Though these may seem like significant numbers, it is important to remember that the majority of elevated platelet counts are caused by a reactive process, such . Second opinion] I had elevated platelet count of 447 in November got referred to a hematologist and my blood work came back normal but i had elevated total protein and ALT, calcium was on the normal b . If you just got over a bad infection, your platelet count will be higher. Medication. It can have many reasons, but two most common are that the cells produce more platelets and that the spleen removes less platelets from the body. Could endometriosis cause a slightly elevated platelet count? The highest has been 526,000. Treatment Reactive thrombocytosis. This is usually because there's a problem with one of the genes that control the making of platelets. A reaction to a disease. It means your body is making too many platelets. Here are some causes of secondary high platelet count: Infection (acute and chronic) Inflammatory disorders (eg Kawasaki's disease) Chronic iron deficiency. Your Platelets value of 432 x10E3/uL is too high. Abstract. In a normal CBC, the Platelet Count can range from 130k to 400K. high platelet level (thrombocytosis) more than 450,000. normal platelet level. An elevated platelet count is known as thrombocytosis. An elevated platelet count is known as thrombocytosis. Sometimes blood-forming cells just make too many platelets. 4.8k views Answered >2 years ago. A photomicrograph of the peripheral blood film is shown. On a clinical level, thrombocytosis is classified "mild" at a platelet count between >500,000 μL and <700,000 μL; "m … Sometimes blood-forming cells just make too many platelets. A good Platelets is usually between 140 and 415 x10E3/uL. Elevated platelet counts are often an incidental or unexpected finding on a complete blood count (CBC . Complete Blood Count. Metabolic syndrome patients are insulin resistant, often hypertensive, and at high cardiovascular disease risk, yet the relationship of platelets to the metabolic syndrome is unknown. Moderately high platelet counts such as yours sometimes means that another inflammatory disease or infection is ongoing. As platelets course through the vasculature of inflamed tissue, they are exposed to soluble mediators such as lipid mediators, cytokines and chemokines released by activated leucocytes, ECs and perivascular cells (Fig. She has been labeled as "failing to thrive."So far, tests haven't come up with anything but a slightly elevated platelet count of 455 (although her pediatrician said that her results were all "normal"). I had a platelet function test with normal results this year, but my internist would like me to see a hematologist for the first time, the appointment is in 3 weeks. If you are concerned, I would ask your dr. about your count being slightly elevated. The condition needs to be dealt with utmost care and attention . Too many platelets is called thrombocytosis. Determine the platelet count at which patients exceed a 3% risk of cancer We will do this by examining electronic medical records of patients with a platelet count in the normal range, and cancer registry records. Platelet and white blood cell counts are higher among some insulin-resistant patients and may contribute to atherothromboembolic complications. Do you mean platelets were only 1,400 or 1.4 million. However, some studies . The clinical features can relate to an increased incidence of arterial . Hematology and Oncology 30 years experience. High platelet count: There are many causes for a high platelet count. Platelets as a target in inflammation. low platelet count (30 to 50): you might bruise more easily and bleed for longer if you cut yourself. The platelet count is used to diagnose disease and to help determine the cause of excess bleeding or clotting. His platelet count steadily increased to 500,000/L by day 6 and 812,000/L by day 8. Treatment Reactive thrombocytosis. Normal platelet counts are in the range of 150,000 to 400,000 per microliter (or 150 - 400 x 109 per liter), but the normal range for the platelet count varies slightly among different laboratories. Thrombocytosis is the medical term used to describe the display of elevated platelet count. Primary thrombocytosis, or essential thrombocythemia, can cause serious bleeding or clotting complications. Low platelet count is known as thrombocytopenia. This analysis helps you to check if your Platelets value is within normal range. A peripheral smear revealed an increased number of platelets but no morphologic abnormalities. MPNs are very very rare. Treatment for this condition depends on the cause. Our health systems are a little different but our health problems are exactly the same. A 36-year-old member asked: What causes a high platelet count? Platelets count of a child in the age 6 and 7 years should be between (176-452) to be normal count and exclude thrombotic diseases related to platelets deficiency. A high platelet count can be caused by: A problem with blood-forming cells. The problem. In healthy pediatric subjects normal count platelet ranges between 250,000 μL and 450,000 μL. 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